University of Duhok (UoD)

Academic Staff

Oct. 23, 2025, 12:53 p.m.

Degrees Awarded

Post-Doc in Neuroscience, Federal University of Sao Paulo (UIFESP, 2012), Brazil
PhD in Molecular Pharmacology, University of Sao Paulo (USP, 2005), Brazil
MSc in Biochemistry, Federal University of Parana (UFPR, 1999), Brazil
BSc in Pharmacy and Biochemistry, Federal University of Parana (UFPR, 1997), Brazil

Teaching Experience

2017-present: University of Dohuk, College of Pharmacy, Department of Medicinal Chemistry, Iraq

2012-2014: Lutheran University of Brazil (ULBRA), Tocantins, Brazil, College of Pharmacy.

2006/2012: Federal University of Sao Paulo, UNIFESP, Brazil
Department of Neurology and Neurosurgery Visiting Assistant Professor.
Course "Update on Central Nervous System Diseases”.

2000/2005: University Tuiuti of Parana, Parana, Brazil
College of Pharmacy Assistant Professor of Biochemistry, Researcher and Member of the College Council

1998-2000 Federal University of Parana
Visiting Lecturer

Other activities:

2012-2014: College Council Member. Lutheran University of Brazil (ULBRA), College of Pharmacy.

2010: Member of the Evaluation Commission Panel during the XXV Annual Meeting of the Federation of Societies of Experimental Biology - Fesbe.

2003-2005: College Council Member. University Tuiuti of Parana / UTP, Brazil, College of Pharmacy.

2000: Member of the Evaluation Commission of the papers presented at the Eighth Scientific Event Started - EVINCI. Universidade Federal do Paraná / UFPR.

Research Projects:

Present Colaboration: Pronex Thematic Project: A study using the proteomics method in rats submitted to pilocarpine-induced epilepsy after exposure to carisbamate.

Present Colaboration: Proteomic evaluation in the human hippocampus of patients with temporal lobe epilepsy and chronic rats submitted to the pilocarpine epilepsy induction model.

2012-2014: Evaluation of salivary alpha-amylase activity and its correlation with smoking and pharmacotherapy.

2011: Expression of P2X and P2Y purinergic receptors in brain tissue during epileptogenesis: application of interfering methods (RNAi and pharmacological antagonists) in the characterization of the role of these receptors in temporal lobe epilepsy.

2007-2009: Characterization of the purinergic system in temporal lobe epilepsy: an experimental model approach induced by pilocarpine.

2006-2008: Characterization of pro and anti-apoptotic signaling in temporal lobe epilepsy.

2001-2005: Analysis of the expression of genes, proteins and caspase enzymes in skeletal muscle cell culture and in animals submitted to the cancer - induced cachexia model.

1997-1999: Extraction, purification and biochemical characterization of the uratolytic and saccharolytic enzymatic systems of Pfaffian rhabdomyoma (Xanthophyllic dimorphous).

QA and Activities

Period: 2020-present. University of Dohuk, Iraq
- Physiology and Biochemical Markers of Post-traumatic Stress Disorders.
Sub-projects:
1- Title: Correlation between post-traumatic stress disorder and hormonal imbalance in internal displaced people in Kurdistan Region/Iraq. PhD student: Kajeen Hassan Jasin.
2- Title: Post-traumatic stress disorder: analysis of oxidative stress and inflammatory markers in internal displaced people living in Kurdistan region/Iraq. PhD student: Husni Muhammed Hasan.

Co-supervisions:
Period: 2017-2021. University of Dohuk, Iraq
Thesis: Cholinesterase inhibition and its association with oxidative stress in type 2 diabetic patients. PhD student: Hussein Mohammed Rashid.
Period: 2018-2019
Thesis: Biochemical and genotoxic effect of aspartame or sodium saccharin with or without vitamin C or vitamin E in rats. PhD student: Omar Hassan Aziz Ali.

2010-2012 Federal University of Sao Paulo, UNIFESP, SP, Brazil
Co-Supervision :
Michelle Gasparetti Lima: PhD in Neuroscience
Thesis: Study of the role of P2X7 and P2Y1 receptors through blockade with specific antagonists in pilocarpine-induced epileptogenesis.
Rebeca Padrão Amorim: PhD in Neuroscience Application of the RNA interference method in the characterization of the role of P2X7 receptor in temporal lobe epilepsy.

2007-2009 Federal University of Sao Paulo, UNIFESP, SP, Brazil Supervisions:
Danielli Souza Speciali: undergraduate research Study of the expression of purinergic P2X receptors in the hippocampus of patients with temporal lobe epilepsy. Priscilla Lima: undergraduate research Evaluation of neuronal death and HSP 72 expression in the brain of developing rats submitted to three episodes of status epilepticus by pilocarpine.

Research

1- Impact of Long-Term Cyclamate and Saccharin Consumption on Biochemical Parameters in Healthy Individuals and Type 2 Diabetes Mellitus Patients. Medicina. 2023 Apr 3;59(4):698.

2- Adenosine A1 Receptor Agonist (R-PIA) before Pilocarpine Modulates Pro-and Anti-Apoptotic Factors in an Animal Model of Epilepsy. Pharmaceuticals 14.4 (2021): 376.

3- Serendipitous discovery of phenylketonuria in Iraq–How to identify and treat? Molecular Genetics and Metabolism Reports. 2021 Jun;27.

4- In vitro inhibition of blood cholinesterases by the organophosphate dichlorvos in typ-2 diabetic patients. Indian Journal of Forensic Medicine & Toxicology. 2021 May 17;15(3):3119-24.

5- Blood cholinesterase activity and oxidative stress in type 2 diabetic patients. Rashid HM. Duhok medical journal. 2021 Apr 27;15(1):48-57.

6- Challenges of post-traumatic stress disorder (PTSD) in Iraq: biochemical network and methodologies. A brief review. Horm Mol Biol Clin Investig. 2020 Nov 6;41(4). doi: 10.1515/hmbci-2020-0037. PMID: 33155990.

Protein biochemistry (enzymology and proteomics), cell signaling and apoptosis, and biochemistry of neurological diseases. Search of new pharmacological active compounds obtained from medicinal plants. Currently has also been dedicated to the scientific advocacy of patients with rare metabolic diseases in Iraq.